a. HMG coA
reductase
b HMG coA lyase
c HMG coA synthase
d. Thiolase
answer -HMG CoA
Synthase

Acetoacetyl-CoA, which is the starting material for ketogenesis, also arises directly from the terminal fourcarbons of a fatty acid -oxidation(Figure 22–7). Condensation of acetoacetyl-CoA with another molecule of
acetyl-CoA by 3-hydroxy-3-methylglutaryl-CoA synthase forms 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA)[Harper28th Chapter 22]Diagram 22-7
Expl-Acetoacetyl Co A is the starting material for ketogenesis..Acetyl CoA released by Oxidation is added to the AcetoAcetyl Co A To Form HMG CoA.So Thiolasecannot be considered a part of Ketogenesis according to Harper.
But many books says Acetyl CoA is the staarting material.But Harper doesnt.
Cholesterol Synthesis
Ketogenesis
Acetoacetyl-CoA, which is the starting material for ketogenesis, also arises directly from the terminal fourcarbons of a fatty acid -oxidation(Figure 22–7). Condensation of acetoacetyl-CoA with another molecule of
acetyl-CoA by 3-hydroxy-3-methylglutaryl-CoA synthase forms 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA)[Harper28th Chapter 22]Diagram 22-7
Expl-Acetoacetyl Co A is the starting material for ketogenesis..Acetyl CoA released by Oxidation is added to the AcetoAcetyl Co A To Form HMG CoA.So Thiolasecannot be considered a part of Ketogenesis according to Harper.
But many books says Acetyl CoA is the staarting material.But Harper doesnt.
i find these really useful mam..thank u very much mam..
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