13.Third generation of thyroid function tests minimum value of assay TSH value is

 a.   .4 IU/ml

b  .    .04IU/ml

c.      .004IU/ml

d.   004IU/ml

 

 Utility of third generation thyrotropin assays in thyroid function testing.

Saller B, Broda N, Heydarian R, Görges R, Mann K.

Source

Department of Internal Medicine, University of Essen, Germany. bernhard.saller@uni-essen.de

Abstract

Determination of thyrotropin (TSH) by sensitive immunometric assays is currently judged as the most sensitive and also most cost-effective first-line approach to thyroid function testing. Further improvement of assay sensitivity has led to the description of third generation TSH assays with a functional sensitivity in the range of 0.01 to 0.02 mU/l

Third generation TSH assays have become available with detection limits of about 0.01 mU/L. Because of the considerably lower detection limit, these assays can reliably distinguish between normal and hyperthyroid patients(Boulder Medical Center Journal)

These are the refernces I could collect.Please contribute more details

Extremely sensitive (fourth-generation) assays can detect TSH levels  0.004 mU/L, but, for practical purposes, assays sensitive to 0.1 mU/L are sufficient[Harrison 18^th editione book Chapter 341]